Using computation to explore the natural world
Location: King Henry Building
Our Sequencing and Bioinformatics laboratory is the hub for working with a variety of DNA and RNA sequencing tools, as well as high-throughput nanopore sequencers.
Through hands-on experiments, you'll see how DNA and RNA pass through tiny pores and are then decoded into their constituent parts by machine learning algorithms.
The facility includes a wide range of computational tools to analyse nanopore sequencing data and other next-generation sequencing platforms. Additionally, we maintain pipelines for sequencing applications such as whole (meta) genome assemblies, RNA sequences, targeted sequences, and amplicon sequences.
Our lab collaborates on a wide range of research projects, especially those that use and (ONT) for high-throughput sequencing, and has recently served as a virus Genomics UK (COG-UK) . We also host a range of research projects within the Centre for Enzyme Innovation (CEI), exploring the genomes of naturally occurring microorganisms to identifying enzymes with potential industrial applications.
Equipment and amenities
- MinION nanopore sequencer (Oxford Nanopore Technologies)
- GridION nanopore sequencer (Oxford Nanopore Technologies)
- P2Solo PromethION nanopore sequencer (Oxford Nanopore Technologies)
- VolTrax automatic sample preparation (Oxford Nanopore Technologies)
- Qubit 4 fluorometer (Invitrogen)
- DS-11 Spectrophotomer (Denovix)
- 4150 TapeStation (Agilent)
- Bioinformatics High Performance Computing (HPC) cluster, which includes:
- Four 24-CPU compute nodes with 768 GB RAM
- Two 24-CPU compute nodes with 384GB RAM
- One GPU compute node with two V100 Tesla GPUs and 1,024 GB RAM
- One head node with 48 CPUs and 384 GB RAM
- One PB of redundant data storage connected via a 10GbE Network
Contact us
If you're interested in our sequencing and bioinformatics facilities – please email seqandbio@port.ac.uk or call +44 (0) 23 9284 2043.
Related facilities
Biophysical laboratories
Use professional-standard equipment to explore how the structures and functions of molecules change under different conditions.
Institute of Life Sciences and Healthcare
We're exploring disciplinary boundaries to discover, understand and develop knowledge for the benefit of the environment and humankind.
Centre for Enzyme Innovation
At the Centre for Enzyme Innovation, we are working to solve one of the most pressing environmental issues facing our planet.
Related courses
Where to find us
Sequencing and Bioinformatics Group laboratory
King Henry Building
King Henry I Street
1024ºË¹¤³§
PO1 2DY